Article
Genetic variants in central metabolic genes influence some but not all relations of inflammatory markers in a collective with polycystic ovary syndrome.
Archives of physiology and biochemistry - 1 Oct 2012
Knebel Birgit, Lehr Stefan, Janssen Onno E, Hahn Susanne, Nitzgen Ulrike, Jacob Sylvia, Haas Jutta, Muller-Wieland Dirk, Kotzka Jorg
Abstract excerpt
Patients with polycystic ovary syndrome (PCOS) suffer, in addition to reproductive disturbances, from symptoms of the metabolic syndrome like insulin resistance, elevated coronary risk and visceral obesity. Genes with confirmed associations to the metabolic syndrome are also candidate genes for a relationship to metabolic parameters of the PCOS syndrome. The study presented indicates that genetic variants of the...
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