Article
Lack of association between LXRα and LXRβ gene polymorphisms and prevalence of metabolic syndrome: a case-control study of an Iranian population.
Gene - 15 Dec 2013
Rooki Hassan, Ghayour-Mobarhan Manjid, Haerian Monir-Sadat, Ebrahimi Mahmoud, Azimzadeh Pedram, Heidari-Bakavoli Alireza, Mirfakhraei Reza, Tavallaie Shima, Mirhafez Reza, Ferns Gordon, Zali Mohammad-Reza
Abstract excerpt
The metabolic syndrome (MetS) is considered to be a major risk factor for type 2 diabetes mellitus and cardiovascular diseases. It is characterized by central adiposity, high blood pressure, glucose intolerance and abnormalities of lipoprotein metabolism. The cause of MetS is likely to be due to a complex interaction between genetic and environmental factors. Liver X receptors alpha (NR1H3) and beta (NR1H2) play...
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