Article
54G/C polymorphism of SREBF-1 gene is associated with polycystic ovary syndrome.
European journal of obstetrics, gynecology, and reproductive biology - 1 May 2015
Li Lan, Yun Ji-Hyun, Ryoo Ji Eun, Lee Kyung-Ju, Choi Bum-Chae, Baek Kwang-Hyun
Abstract excerpt
OBJECTIVE: A sterol regulatory element-binding protein (SREBF-1) transcription factor is a major regulator of lipid metabolism, carbohydrate, and plays a key role in energy homeostasis. The 54(G/C) polymorphism of SREBF-1 gene was reported that it is related with metabolic diseases including obesity, type 2 diabetes, and dyslipidemia. Among these, polycystic ovary syndrome (PCOS) is known as a common...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
