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Article

Polymorphisms in the IRS-1 and PPAR-γ genes and their association with polycystic ovary syndrome among South Indian women.

Gene - 15 Jul 2012

Dasgupta Shilpi, Sirisha Pisapati, Neelaveni Kudugunti, Anuradha Katragadda, Sudhakar Godi, Reddy B Mohan

Abstract excerpt

Polycystic ovary syndrome is known to be characterized by metabolic abnormalities such as hyperinsulinemia, adiposity and dyslipidemia. Both insulin receptor substrate-1 and peroxisome proliferator-activated receptor-γ have emerged as significant candidate genes in the pathogenesis of PCOS. In this study, we report for the first time, the association pattern of these genes with PCOS among South Indian women. Two...

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Identifiers

PMID: 22575725
DOI: 10.1016/j.gene.2012.04.060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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