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Article

The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review.

Molecular biology reports - 1 May 2012

Ma Jiexian, Wu Min

Abstract excerpt

To explore the relationship of Notch1 mutation in T-ALL with the survival rate of T-ALL patients. The PubMed database, the Cochrane Library, conference proceedings, EMBASE databases, and references of published trials and review articles were searched. Two reviewers independently assessed the quality of the trials and extracted data. Hazard ratios (HRs) for event-free survival (EFS) were pooled by STATA package....

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Source

Identifiers

PMID: 22311010
DOI: 10.1007/s11033-011-1424-8

Genes

EFS
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The indicative effect of Notch1 expression for the prognosis of T-cell acute lymphocytic leukemia: a systematic review.PMID 22311010Read ↗

Progress in research on childhood T-cell acute lymphocytic leukemia, Notch1 signaling pathway, and its inhibitors: A reviewSemantic proximity Read ↗

Significance of NOTCH1 mutations détections in T-acute lymphoblastic leukemia patients.Semantic proximity Read ↗

NOTCH1 mutation status as a prognostic biomarker in T-cell acute lymphoblastic leukemia: a systematic review and meta-analysis.Semantic proximity Read ↗

Friend or foe: can activating mutations in NOTCH1 contribute to a favorable treatment outcome in patients with T-ALL?Semantic proximity Read ↗

<i>NOTCH1</i> Mutations in T-Cell Acute Lymphoblastic Leukemia: Prognostic Significance and Implication in Multifactorial LeukemogenesisSemantic proximity Read ↗

NOTCH1 mutations are associated with favourable long-term prognosis in paediatric T-cell acute lymphoblastic leukaemia: a retrospective study of patients treated on BCH-2003 and CCLG-2008 protocol in China.Semantic proximity Read ↗

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.Semantic proximity Read ↗

Kick it up a Notch: NOTCH1 activation in T-ALL.Semantic proximity Read ↗

Notch signaling in T-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

[The role and research progress of NOTCH1 in T-cell acute lymphoblastic leukemia].Semantic proximity Read ↗

Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.Semantic proximity Read ↗

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