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Article

Weighted selective collapsing strategy for detecting rare and common variants in genetic association study.

BMC genetics - 6 Feb 2012

Dai Yilin, Jiang Renfang, Dong Jianping

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have been used successfully in detecting associations between common genetic variants and complex diseases. However, common SNPs detected by current GWAS only explain a small proportion of heritable variability. With the development of next-generation sequencing technologies, researchers find more and more evidence to support the role played by rare variants in...

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PMID: 22309429
DOI: 10.1186/1471-2156-13-7
PMCID: PMC3296579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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