Article
Extensive X-linked adaptive evolution in central chimpanzees.
Proceedings of the National Academy of Sciences of the United States of America - 7 Feb 2012
Hvilsom Christina, Qian Yu, Bataillon Thomas, Li Yingrui, Mailund Thomas, Sallé Bettina, Carlsen Frands, Li Ruiqiang, Zheng Hancheng, Jiang Tao, Jiang Hui, Jin Xin, Munch Kasper, Hobolth Asger, Siegismund Hans R, Wang Jun, Schierup Mikkel Heide
Abstract excerpt
Surveying genome-wide coding variation within and among species gives unprecedented power to study the genetics of adaptation, in particular the proportion of amino acid substitutions fixed by positive selection. Additionally, contrasting the autosomes and the X chromosome holds information on the dominance of beneficial (adaptive) and deleterious mutations. Here we capture and sequence the complete exomes of 12...
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