Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extreme selective sweeps independently targeted the X chromosomes of the great apes.

Proceedings of the National Academy of Sciences of the United States of America - 19 May 2015

Nam Kiwoong, Munch Kasper, Hobolth Asger, Dutheil Julien Yann, Veeramah Krishna R, Woerner August E, Hammer Michael F, Mailund Thomas, Schierup Mikkel Heide

Abstract excerpt

The unique inheritance pattern of the X chromosome exposes it to natural selection in a way that is different from that of the autosomes, potentially resulting in accelerated evolution. We perform a comparative analysis of X chromosome polymorphism in 10 great ape species, including humans. In most species, we identify striking megabase-wide regions, where nucleotide diversity is less than 20% of the chromosomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Hominidae

Share to Models, Genetic

Share to Selection, Genetic

Share to Species Specificity

Share to X Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 25941379
DOI: 10.1073/pnas.1419306112
PMCID: PMC4443357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extreme selective sweeps independently targeted the X chromosomes of the great apes.PMID 25941379Read ↗

Extraordinary selection on the human X chromosome associated with archaic admixtureSemantic proximity Read ↗

Evidence that the rate of strong selective sweeps increases with population size in the great apes.Semantic proximity Read ↗

Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence.Semantic proximity Read ↗

Contrasting Patterns of Genomic Diversity Reveal Accelerated Genetic Drift but Reduced Directional Selection on X-Chromosome in Wild and Domestic Sheep Species.Semantic proximity Read ↗

Dynamic evolution of great ape Y chromosomesSemantic proximity Read ↗

Strong selective sweeps before 45,000BP displaced archaic admixture across the human X chromosomeSemantic proximity Read ↗

The Complete Sequence and Comparative Analysis of Ape Sex ChromosomesSemantic proximity Read ↗

Long-term natural selection affects patterns of neutral divergence on the X chromosome more than the autosomesSemantic proximity Read ↗

Admixture has obscured signals of historical hard sweeps in humansSemantic proximity Read ↗

Extensive X-linked adaptive evolution in central chimpanzees.Semantic proximity Read ↗

Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee.Semantic proximity Read ↗

Great ape Y Chromosome and mitochondrial DNA phylogenies reflect subspecies structure and patterns of mating and dispersal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.