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Article

Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee.

Proceedings of the National Academy of Sciences of the United States of America - 15 Mar 2005

Lu Jian, Wu Chung-I

Abstract excerpt

The effect of weak selection driving genome evolution has attracted much attention in the last decade, but the task of measuring the strength of such selection is particularly difficult. A useful approach is to contrast the evolution of X-linked and autosomal genes in two closely related species in a whole-genome analysis. If the fitness effect of mutations is recessive, X-linked genes should evolve more rapidly...

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Identifiers

PMID: 15728731
DOI: 10.1073/pnas.0500436102
PMCID: PMC554819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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