Article
Inference of purifying and positive selection in three subspecies of chimpanzees (Pan troglodytes) from exome sequencing.
Genome biology and evolution - 30 Mar 2015
Bataillon Thomas, Duan Jinjie, Hvilsom Christina, Jin Xin, Li Yingrui, Skov Laurits, Glemin Sylvain, Munch Kasper, Jiang Tao, Qian Yu, Hobolth Asger, Wang Jun, Mailund Thomas, Siegismund Hans R, Schierup Mikkel H
Abstract excerpt
We study genome-wide nucleotide diversity in three subspecies of extant chimpanzees using exome capture. After strict filtering, Single Nucleotide Polymorphisms and indels were called and genotyped for greater than 50% of exons at a mean coverage of 35× per individual. Central chimpanzees (Pan troglodytes troglodytes) are the most polymorphic (nucleotide diversity, θw = 0.0023 per site) followed by Eastern (P. t....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.