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Article

Characterization of SfPgdA, a Shigella flexneri peptidoglycan deacetylase required for bacterial persistence within polymorphonuclear neutrophils.

Microbes and infection - 1 Jul 2012

Kaoukab-Raji Abdelmoughit, Biskri Latéfa, Bernardini Maria-Lina, Allaoui Abdelmounaaïm

Abstract excerpt

Peptidoglycan deacetylases protect the Gram-positive bacteria cell wall from host lysozymes by deacetylating peptidoglycan. Sequence analysis of the genome of Shigella flexneri predicts a putative polysaccharide deacetylase encoded by the plasmidic gene orf185, renamed here SfpgdA. We demonstrate...

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Source

Identifiers

PMID: 22307019
DOI: 10.1016/j.micinf.2012.01.009

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22307019-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Characterization of SfPgdA, a Shigella flexneri peptidoglycan deacetylase required for bacterial persistence within polymorphonuclear neutrophils.PMID 22307019Read ↗

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