A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

doi:10.1073/pnas.0609672104

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Article

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

Proceedings of the National Academy of Sciences of the United States of America - 16 Jan 2007

Boneca Ivo G, Dussurget Olivier, Cabanes Didier, Nahori Marie-Anne, Sousa Sandra, Lecuit Marc, Psylinakis Emmanuel, Bouriotis Vassilis, Hugot Jean-Pierre, Giovannini Marco, Coyle Anthony, Bertin John, Namane Abdelkader, Rousselle Jean-Claude, Cayet Nadège, Prévost Marie-Christine, Balloy Viviane, Chignard Michel, Philpott Dana J, Cossart Pascale, Girardin Stephen E

Abstract excerpt

Listeria monocytogenes is a human intracellular pathogen that is able to survive in the gastrointestinal environment and replicate in macrophages, thus bypassing the early innate immune defenses. Peptidoglycan (PG) is an essential component of the bacterial cell wall readily exposed to the host and, thus, an important target for the innate immune system. Characterization of the PG from L. monocytogenes...

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PMID: 17215377
DOI: 10.1073/pnas.0609672104
PMCID: PMC1766339

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TLR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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