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Article

Significant contribution of the pgdA gene to the virulence of Streptococcus suis.

Molecular microbiology - 1 Dec 2008

Fittipaldi Nahuel, Sekizaki Tsutomu, Takamatsu Daisuke, de la Cruz Domínguez-Punaro María, Harel Josée, Bui Nhat Khai, Vollmer Waldemar, Gottschalk Marcelo

Abstract excerpt

Streptococcus suis is a major swine pathogen and emerging zoonotic agent. In this study we have determined the muropeptide composition of S. suis peptidoglycan (PG) and found, among other modifications, N-deacetylated compounds. Comparison with an isogenic mutant showed that the product of the pgdA gene is responsible for this specific modification which occurred in very low amounts. Low level of PG...

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Identifiers

PMID: 18990186
DOI: 10.1111/j.1365-2958.2008.06463.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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