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Article

The lysozyme-induced peptidoglycan N-acetylglucosamine deacetylase PgdA (EF1843) is required for Enterococcus faecalis virulence.

Journal of bacteriology - 1 Nov 2012

Benachour Abdellah, Ladjouzi Rabia, Le Jeune André, Hébert Laurent, Thorpe Simon, Courtin Pascal, Chapot-Chartier Marie-Pierre, Prajsnar Tomasz K, Foster Simon J, Mesnage Stéphane

Abstract excerpt

Lysozyme is a key component of the innate immune response in humans that provides a first line of defense against microbes. The bactericidal effect of lysozyme relies both on the cell wall lytic activity of this enzyme and on a cationic antimicrobial peptide activity that leads to membrane permeabilization. Among Gram-positive bacteria, the opportunistic pathogen Enterococcus faecalis has been shown to be...

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Identifiers

PMID: 22961856
DOI: 10.1128/JB.00981-12
PMCID: PMC3486378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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