Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population.

doi:10.1016/j.neulet.2017.04.008

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Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population.

Neuroscience letters - 10 May 2017

Sudesh Ravi, Priyadarshini Thirunavukkarasu, Preeti Rajendran, John Sujit, Thara Rangaswamy, Mowry Bryan, Munirajan Arasamabattu Kannan

Abstract excerpt

Schizophrenia (SCZ) as a severe and complex neuropsychiatric disorder and is characterized by positive symptoms, negative symptoms and cognitive dysfunctions. Genome-wide association studies (GWAS) have identified a strong association between the single nucleotide polymorphism (SNP) rs12807809 upstream of Neurogranin (NRGN) in a European population. This evidence prompted us to conduct an association study among...

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PMID: 28389239
DOI: 10.1016/j.neulet.2017.04.008

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NRGN

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