Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the gene encoding neurogranin with schizophrenia in males.

Journal of psychiatric research - 1 Jan 2008

Ruano Dina, Aulchenko Yurii S, Macedo António, Soares Maria J, Valente José, Azevedo Maria H, Hutz Mara H, Gama Clarissa S, Lobato Maria I, Belmonte-de-Abreu Paulo, Goodman Ann B, Pato Carlos, Heutink Peter, Palha Joana A

Abstract excerpt

The neurogranin (NRGN) gene produces a postsynaptic brain-specific protein that regulates calmodulin-Ca(2+) availability in neurons. Acting downstream of the NMDA receptor and upstream of calcineurin and other proteins implicated in schizophrenia, NRGN is a good candidate for association studies in schizophrenia. NRGN expression is regulated during development and is modulated by thyroid hormones and retinoids,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Pool

Share to Genetic Carrier Screening

Share to Introns

Share to Nucleotides

Share to Portugal

Share to Schizophrenia

Source

Identifiers

PMID: 17140601
DOI: 10.1016/j.jpsychires.2006.10.008

Genes

NRGN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the gene encoding neurogranin with schizophrenia in males.PMID 17140601Read ↗

Genetic and functional analysis of the gene encoding neurogranin in schizophrenia.Semantic proximity Read ↗

Analysis of neurogranin (NRGN) in schizophrenia.Semantic proximity Read ↗

Polymorphisms in NRGN are associated with schizophrenia, major depressive disorder and bipolar disorder in the Han Chinese population.Semantic proximity Read ↗

Neuregulin 1 and schizophrenia.Semantic proximity Read ↗

The association between rs12807809 polymorphism in neurogranin gene and risk of schizophrenia: A meta-analysis.Semantic proximity Read ↗

Correlation of rs35753505 polymorphism in Neuregulin 1 gene with psychopathology and intelligence of people with schizophrenia.Semantic proximity Read ↗

Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population.Semantic proximity Read ↗

Influence of the NRGN gene on intellectual ability in schizophrenia.Semantic proximity Read ↗

Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects.Semantic proximity Read ↗

Genetic findings in schizophrenia patients related to alterations in the intracellular Ca-homeostasis.Semantic proximity Read ↗

Family-based association study of neuregulin-1 gene and psychosis in a Spanish sample.Semantic proximity Read ↗

NRG1 and BDNF genes in schizophrenia: an association study in an Italian case-control sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.