Optimization approaches for the in silico discovery of optimal targets for gene over/underexpression.

Abstract excerpt

Metabolic engineering (ME) efforts have been recently boosted by the increase in the number of annotated genomes and by the development of several genome-scale metabolic models for microbes of interest in industrial biotechnology. Based on these efforts, strain optimization methods have been proposed to reach the best set of genetic changes to apply to selected host microbes, in order to create strains that are...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Computer Simulation