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Article

Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease.

Leukemia - 1 Jul 2012

Ma Peilin, Mali Raghuveer Singh, Martin Holly, Ramdas Baskar, Sims Emily, Kapur Reuben

Abstract excerpt

Gain-of-function mutations in KIT receptor in humans are associated with gastrointestinal stromal tumors, systemic mastocytosis and acute myelogenous leukemia. The intracellular signals that contribute to oncogenic KIT-induced myeloproliferative disease (MPD) are poorly understood. Here, we show...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22297723
DOI: 10.1038/leu.2012.22
PMCID: PMC4378686

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22297723-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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