Article
Tumour necrosis factor receptor superfamily member 11B polymorphisms and association with knee osteoarthritis in women.
International journal of immunogenetics - 1 Jun 2012
Hulin-Curtis S L, Bidwell J L, Perry M J
Abstract excerpt
We examined single-nucleotide polymorphisms (SNPs) across the tumour necrosis factor receptor superfamily member 11B (TNFRSF11B) gene and knee OA. We identified alleles in a VNTR region in intron 3 that was observed exclusively in women OA cases (P = 0.007, Pc = 0.042). Our results reveal that a previously unreported association between a VNTR genotype in TNFRSF11B and knee OA in women.
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