Article
Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression.
European journal of oral sciences - 1 Feb 2012
Larsson Lena, Thorbert-Mros Sara, Rymo Lars, Berglundh Tord
Abstract excerpt
Epigenetic modifications of DNA and its associated proteins influence gene expression. The -1087 interleukin-10 (IL10) gene polymorphism is associated with differences in IL10 expression. The objectives of this study were to analyze the effect of DNA methylation and histone modifications on IL10 gene expression, the differences in epigenetic modifications between GG and AA genotypes of the -1087 IL10 gene...
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