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Article

Analysis of the 5' untranslated region (5'UTR) of the alcohol oxidase 1 (AOX1) gene in recombinant protein expression in Pichia pastoris.

Gene - 1 Apr 2012

Staley Chris A, Huang Amy, Nattestad Maria, Oshiro Kristin T, Ray Laura E, Mulye Tejas, Li Zhiguo Harry, Le Thu, Stephens Justin J, Gomez Seth R, Moy Allison D, Nguyen Jackson C, Franz Andreas H, Lin-Cereghino Joan, Lin-Cereghino Geoff P

Abstract excerpt

Pichia pastoris is a methylotrophic yeast that has been genetically engineered to express over one thousand heterologous proteins valued for industrial, pharmaceutical and basic research purposes. In most cases, the 5' untranslated region (UTR) of the alcohol oxidase 1 (AOX1) gene is fused to the coding sequence of the recombinant gene for protein expression in this yeast. Because the effect of the AOX1 5'UTR on...

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Identifiers

PMID: 22285974
DOI: 10.1016/j.gene.2012.01.006
PMCID: PMC3464313

Genes

AOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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