Article
Beyond silencing--engineering applications of RNA interference and antisense technology for altering cellular phenotype.
Current opinion in biotechnology - 1 Oct 2008
Hebert Colin G, Valdes James J, Bentley William E
Abstract excerpt
Since its discovery 10 years ago, RNA interference (RNAi) has evolved from a research tool into a powerful method for altering the phenotype of cells and whole organisms. Its near universal applicability coupled with its pinpoint accuracy for suppressing target proteins has altered the landscape of many fields. While there is considerable intellectual investment in therapeutics, its potential extends far beyond....
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