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Article

Diurnal expression of the thrombopoietin gene is regulated by CLOCK.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2012

Tracey C J, Pan X, Catterson J H, Harmar A J, Hussain M M, Hartley P S

Abstract excerpt

BACKGROUND: Most physiologic processes exhibit diurnal fluctuations controlled by the circadian regulation of sleep-wake behavior and feeding cycles. In addition, many cell types express endogenous circadian rhythms that affect cell-specific processes. Independent reports support the hypothesis that thrombopoietin (TPO) is under circadian control. OBJECTIVES: The current study tested the hypothesis that CLOCK, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22284746
DOI: 10.1111/j.1538-7836.2012.04643.x

Genes

CLOCK
TPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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