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Article

Hepatic Thrombopoietin mRNA Is Increased in Acute Inflammation

1 Jan 2001

Abstract excerpt

The plasma concentration of thrombopoietin (TPO) in general is inversely related to the mass of platelets and megakaryocytes. However, reactive thrombocytosis of inflammatory disease is accompanied by elevated TPO levels. To investigate whether the rate of TPO mRNA expression is altered during acute inflammation, rats were injected with bacterial lipopolysaccharide (LPS). After 6 h, total RNA from liver and...

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PMID: 11776309
DOI: 10.1055/s-0037-1616745

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