Article
Circadian variations in coagulation and fibrinolytic factors among four different strains of mice.
Chronobiology international - 1 Jan 2007
Ohkura Naoki, Oishi Katsutaka, Sakata Toshiyuki, Kadota Koji, Kasamatsu Manami, Fukushima Nanae, Kurata Ayako, Tamai Yoko, Shirai Hidenori, Atsumi Gen-ichi, Ishida Norio, Matsuda Juzo, Horie Shuichi
Abstract excerpt
This study examined circadian variation in coagulation and fibrinolytic parameters among Jcl:ICR, C3H/HeN, BALB/cA, and C57BL/6J strains of mice. Plasma plasminogen activator inhibitor 1 (PAI-1) levels fluctuated in a circadian manner and peaked in accordance with the mRNA levels at the start of the active phase in all strains. Fibrinogen mRNA levels peaked at the start of rest periods in all strains, although...
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