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Article

Expression pattern of circadian genes and steroidogenesis-related genes after testosterone stimulation in the human ovary

10 Sept 2016

Abstract excerpt

BACKGROUND: Previous studies have shown that circadian genes might be involved in the development of polycystic ovarian syndrome (PCOS). Hyperandrogenism is a hallmark feature of PCOS. However, the effect of hyperandrogenism on circadian gene expression in human granulosa cells is unknown, and the general expression pattern of circadian genes in the human ovary is unclear. METHODS: Expression of the circadian...

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Share to Circadian rhythm and melatonin
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PMID: 27614897
DOI: 10.1186/s13048-016-0264-5

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