Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inter-chromosomal level of genome organization and longevity-related phenotypes in humans.

Age (Dordrecht, Netherlands) - 1 Apr 2013

Kulminski Alexander M, Culminskaya Irina, Yashin Anatoli I

Abstract excerpt

Studies focusing on unraveling the genetic origin of health span in humans assume that polygenic, aging-related phenotypes are inherited through Mendelian mechanisms of inheritance of individual genes. We use the Framingham Heart Study (FHS) data to examine whether non-Mendelian mechanisms of inheritance can drive linkage of loci on non-homologous chromosomes and whether such mechanisms can be relevant to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Chi-Square Distribution
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genome, Human

Share to Inheritance Patterns

Share to Linkage Disequilibrium

Share to Longevity

Source

Open in PubMed Open full text

Identifiers

PMID: 22282054
DOI: 10.1007/s11357-011-9374-6
PMCID: PMC3592956

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inter-chromosomal level of genome organization and longevity-related phenotypes in humans.PMID 22282054Read ↗

Complex phenotypes and phenomenon of genome-wide inter-chromosomal linkage disequilibrium in the human genome.Semantic proximity Read ↗

Genomics of human health and aging.Semantic proximity Read ↗

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.Semantic proximity Read ↗

Power of non-parametric linkage analysis in mapping genes contributing to human longevity in long-lived sib-pairs.Semantic proximity Read ↗

Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges.Semantic proximity Read ↗

LongevityMap: a database of human genetic variants associated with longevity.Semantic proximity Read ↗

NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes.Semantic proximity Read ↗

Identification of 12 genetic loci associated with human healthspanSemantic proximity Read ↗

Genetic variation and human longevity.Semantic proximity Read ↗

Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality.Semantic proximity Read ↗

HapMap and mapping genes for cardiovascular disease.Semantic proximity Read ↗

Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.