Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Road Map for Those Who Don't Know JAK-STAT

31 May 2002

Abstract excerpt

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway transmits information received from extracellular polypeptide signals, through transmembrane receptors, directly to target gene promoters in the nucleus, providing a mechanism for transcriptional regulation without second messengers. Evolutionarily conserved in eukaryotic organisms from slime molds to humans, JAK-STAT signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 14-3-3 protein interactions
Share to Fungal Biology and Applications
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12040185
DOI: 10.1126/science.1071545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Road Map for Those Who Don't Know JAK-STATPMID 12040185Read ↗

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic InterventionSemantic proximity Read ↗

Signaling by STATs.Semantic proximity Read ↗

Biology and significance of the JAK/STAT signalling pathways.Semantic proximity Read ↗

STAT Transcription Factors in T Cell Control of Health and Disease.Semantic proximity Read ↗

Series Introduction: JAK-STAT signaling in human diseaseSemantic proximity Read ↗

JAKS AND STATS: Biological ImplicationsSemantic proximity Read ↗

STATs: An Old Story, Yet Mesmerizing.Semantic proximity Read ↗

Responses to Cytokines and Interferons that Depend upon JAKs and STATs.Semantic proximity Read ↗

The Janus kinases (Jaks)Semantic proximity Read ↗

The two faces of Janus kinases and their respective STATs in mammary gland development and cancerSemantic proximity Read ↗

Malignant JAK-signaling: at the interface of inflammation and malignant transformationSemantic proximity Read ↗

The Jak-Stat Pathway: Cytokine Signalling from the Receptor to the NucleusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.