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Article

Effects of length and position of an extended linker on sequence-selective DNA recognition of zinc finger peptides.

Biochemistry - 23 Dec 2003

Nomura Wataru, Sugiura Yukio

Abstract excerpt

Engineered zinc finger proteins revealed that a linker sequence connecting zinc finger units has a significant effect on the DNA binding property of the protein. The recognition for a noncontiguous DNA target beyond the current recognition code of zinc finger proteins has never been determined because of the limitation of a zinc finger framework. DNA recognition of zinc finger proteins is limited only to a...

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PMID: 14674754
DOI: 10.1021/bi035446h

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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