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Article

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance

29 Jan 2021

Abstract excerpt

Significance Statement Although the role of the podocyte cytoskeleton in the integrity of glomerular filtration is well established, the specific contribution of an upstream regulatory network comprising the Rho family of small GTPases—modulators of the actin cytoskeleton—is poorly characterized. The authors provide a comprehensive map of the podocyte Rho GTPase affinity interactome and identify a small...

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PMID: 33514561
DOI: 10.1681/asn.2020081126

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