Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of Hepatitis B Virus Replication by the Interferon-Inducible MxA Protein

15 Mar 2001

Abstract excerpt

Human MxA is an alpha/beta interferon-inducible intracytoplasmic protein that mediates antiviral activity against several RNA viruses. We had previously shown that overexpression of the hepatitis B virus (HBV) capsid led to selective downregulation of MxA gene expression, suggesting a mechanism by which the virus escapes from the host defense system (O. Rosmorduc, H. Sirma, P. Soussan, E. Gordien, P. Lebon, M....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Hepatitis Viruses Studies and Epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11222692
DOI: 10.1128/jvi.75.6.2684-2691.2001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of Hepatitis B Virus Replication by the Interferon-Inducible MxA ProteinPMID 11222692Read ↗

Inhibition of interferon-inducible MxA protein expression by hepatitis B virus capsid protein.Semantic proximity Read ↗

MxA inhibits hepatitis B virus replication by interaction with hepatitis B core antigenSemantic proximity Read ↗

Hepatitis B virus downregulates the human interferon-inducible MxA promoter through direct interaction of precore/core proteinsSemantic proximity Read ↗

GTPase activity is not essential for the interferon-inducible MxA protein to inhibit the replication of hepatitis B virus.Semantic proximity Read ↗

The Human Interferon-Induced MxA Protein Inhibits Early Stages of Influenza A Virus Infection by Retaining the Incoming Viral Genome in the CytoplasmSemantic proximity Read ↗

Control of hepatitis B virus at the level of transcriptionSemantic proximity Read ↗

Inhibition of a Large Double-Stranded DNA Virus by MxA ProteinSemantic proximity Read ↗

Inhibition of Coxsackievirus B4 Replication in Stably Transfected Cells Expressing Human MxA ProteinSemantic proximity Read ↗

Hepatitis delta virus proteins repress hepatitis B virus enhancers and activate the alpha/beta interferon-inducible MxA geneSemantic proximity Read ↗

Promoted Cell Death of Cells Expressing Human MxA by Influenza Virus InfectionSemantic proximity Read ↗

Human MxA Protein Confers Resistance to Semliki Forest Virus and Inhibits the Amplification of a Semliki Forest Virus-Based Replicon in the Absence of Viral Structural ProteinsSemantic proximity Read ↗

Human MxA protein participates to the interferon-related inhibition of hepatitis B virus replication in female transgenic miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.