Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of interferon-inducible MxA protein expression by hepatitis B virus capsid protein.

The Journal of general virology - 1 May 1999

Rosmorduc O, Sirma H, Soussan P, Gordien E, Lebon P, Horisberger M, Br Chot C, Kremsdorf D

Abstract excerpt

Chronic hepatitis B treatment has been significantly improved by interferon (IFN) treatment. However, some studies have suggested that hepatitis B virus (HBV) might have a direct effect on the resistance to IFN. Defective particles, generated by spliced HBV RNA and associated with chronic hepatitis B, have been previously characterized; expression of these particles leads to cytoplasmic accumulation of the capsid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Capsid
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Viral

Share to GTP-Binding Proteins

Share to Interferons

Share to Luciferases

Share to Myxovirus Resistance Proteins

Source

Identifiers

PMID: 10355772
DOI: 10.1099/0022-1317-80-5-1253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of interferon-inducible MxA protein expression by hepatitis B virus capsid protein.PMID 10355772Read ↗

Inhibition of Hepatitis B Virus Replication by the Interferon-Inducible MxA ProteinSemantic proximity Read ↗

MxA inhibits hepatitis B virus replication by interaction with hepatitis B core antigenSemantic proximity Read ↗

Hepatitis B virus downregulates the human interferon-inducible MxA promoter through direct interaction of precore/core proteinsSemantic proximity Read ↗

Hepatitis delta virus proteins repress hepatitis B virus enhancers and activate the alpha/beta interferon-inducible MxA geneSemantic proximity Read ↗

Class A capsid assembly modulator apoptotic elimination of hepatocytes with high HBV core antigen level in vivo is dependent on de novo core protein translationSemantic proximity Read ↗

Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive HybridizationSemantic proximity Read ↗

Inhibition of Hepatitis C Virus Production by Aptamers against the Core ProteinSemantic proximity Read ↗

MxA induction may predict sustained virologic responses of chronic hepatitis B patients with IFN-alpha treatment.Semantic proximity Read ↗

Tumor Necrosis Factor Alpha Inhibition of Hepatitis B Virus Replication Involves Disruption of Capsid Integrity through Activation of NF-κBSemantic proximity Read ↗

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosomeSemantic proximity Read ↗

Characterization of microRNA expression profiles associated with hepatitis B virus replication and clearance in vivo and in vitroSemantic proximity Read ↗

Inhibition of a Large Double-Stranded DNA Virus by MxA ProteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.