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Article

Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegans.

Genetics - 1 Apr 2012

Meneely Philip M, McGovern Olivia L, Heinis Frazer I, Yanowitz Judith L

Abstract excerpt

Mutations in the him-5 gene in Caenorhabditis elegans strongly reduce the frequency of crossovers on the X chromosome, with lesser effects on the autosomes. him-5 mutants also show a change in crossover distribution on both the X and autosomes. These phenotypes are accompanied by a delayed entry into pachytene and premature desynapsis of the X chromosome. The nondisjunction, progression defects and desynapsis can...

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Identifiers

PMID: 22267496
DOI: 10.1534/genetics.111.137463
PMCID: PMC3316641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegans.PMID 22267496Read ↗

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