Article
Meiotic mutants that cause a polar decrease in recombination on the X chromosome in Caenorhabditis elegans.
Genetics - 1 Jan 1994
Broverman S A, Meneely P M
Abstract excerpt
Recessive mutations in three autosomal genes, him-1, him-5 and him-8, cause high levels of X chromosome nondisjunction in hermaphrodites of Caenorhabditis elegans, with no comparable effect on autosomal disjunction. Each of the mutants has reduced levels of X chromosome recombination, correlating with the increase in nondisjunction. However, normal or elevated levels of recombination occur at the end of the X...
Topics
- Alleles
- Animals
- Biological Evolution
- Caenorhabditis elegans
- Crosses, Genetic
- Disorders of Sex Development
- Genes, Recessive
- Genetic Complementation Test
- Genetic Linkage
- Models, Genetic
- Mutation