Article
Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells.
Microvascular research - 1 May 2012
He Tongrong, Katusic Zvonimir S
Abstract excerpt
Existing evidence suggests that brain-derived neurotrophic factor (BDNF) promotes survival and proliferation of endothelial cells, stimulates mobilization of hematopoietic progenitors, and induces angiogenesis in ischemic tissues. However, the mechanisms underlying vascular protective function of BDNF are poorly understood. We hypothesized that BDNF increases antioxidant capacity of circulating angiogenic cells....
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