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Article

Human endothelial progenitor cells tolerate oxidative stress due to intrinsically high expression of manganese superoxide dismutase.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2004

He Tongrong, Peterson Timothy E, Holmuhamedov Ekhson L, Terzic Andre, Caplice Noel M, Oberley Larry W, Katusic Zvonimir S

Abstract excerpt

OBJECTIVE: Endothelial progenitor cells (EPCs) display a unique aptitude to promote angiogenesis and restore endothelial function of injured vessels. How progenitor cells can execute a regenerative program in the unfavorable environment of injury/inflammation-induced oxidative stress is poorly understood. We hypothesized that EPCs are resistant to oxidative stress and that this resistance is due to high...

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Identifiers

PMID: 15319267
DOI: 10.1161/01.ATV.0000142810.27849.8f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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