Article
Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors.
Experimental neurology - 1 Mar 2009
Arien-Zakay Hadar, Lecht Shimon, Bercu Marian M, Tabakman Rinat, Kohen Ron, Galski Hanan, Nagler Arnon, Lazarovici Philip
Abstract excerpt
Human umbilical cord blood (HUCB) is a valuable source for cell therapy since it confers neuroprotection in stroke animal models. However, the responsible sub-populations remain to be established and the mechanisms involved are unknown. To explore HUCB neuroprotective properties in a PC12 cell-based ischemic neuronal model, we used an HUCB mononuclear-enriched population of collagen-adherent cells, which can be...
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