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Article

Hypoxia induces angiogenic factors in brain microvascular endothelial cells.

Microvascular research - 1 Mar 2012

Luo J, Martinez J, Yin X, Sanchez A, Tripathy D, Grammas P

Abstract excerpt

Hypoxia is increasingly recognized as an important contributing factor to the development of brain diseases such as Alzheimer's disease (AD). In the periphery, hypoxia is a powerful regulator of angiogenesis. However, vascular endothelial cells are remarkably heterogeneous and little is known about how brain endothelial cells respond to hypoxic challenge. The objective of this study is to characterize the effect...

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Share to Angiogenic Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heme Oxygenase (Decyclizing)

Share to Hypoxia-Inducible Factor 1, alpha Subunit

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Share to Neovascularization, Physiologic

Share to Thrombospondins

Source

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Identifiers

PMID: 22100491
DOI: 10.1016/j.mvr.2011.11.004
PMCID: PMC3278542

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