Article
XIer2 is required for convergent extension movements during Xenopus development.
The International journal of developmental biology - 1 Jan 2011
Hong Sung-Kook, Tanegashima Kosuke, Dawid Igor B
Abstract excerpt
Immediate early response 2 (Ier2) is a downstream target of fibroblast growth factor (FGF) signaling. In zebrafish, Ier2 is involved in left-right asymmetry establishment and in convergent extension movements. We isolated the Xenopus ier2 gene based on sequence similarity searches using multiple vertebrate species. Xenopus Ier2 has high homology in the N-terminal region to other vertebrate Ier2 proteins, and...
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