Transcriptional de-repression and Mfd are mutagenic in stressed Bacillus subtilis cells.

Abstract excerpt

In recent years, it has been proposed that conflicts between transcription and active chromosomal replication engender genome instability events. Furthermore, transcription elongation factors have been reported to prevent conflicts between transcription and replication and avoid genome instability. Here, we examined transcriptional de-repression as a genetic diversity-producing agent and showed, through the use...

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