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Article

RETRACTED: Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.

Science (New York, N.Y.) - 9 Mar 2001

Stein E, Tessier-Lavigne M

Abstract excerpt

Axonal growth cones that cross the nervous system midline change their responsiveness to midline guidance cues: They become repelled by the repellent Slit and simultaneously lose responsiveness to the attractant netrin. These mutually reinforcing changes help to expel growth cones from the midlin...

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Source

Identifiers

PMID: 11239147
DOI: 10.1126/science.1058445

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11239147-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RETRACTED: Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.PMID 11239147Read ↗

Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion.Semantic proximity Read ↗

Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.Semantic proximity Read ↗

A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance.Semantic proximity Read ↗

Short-range and long-range guidance by slit and its Robo receptors. Robo and Robo2 play distinct roles in midline guidance.Semantic proximity Read ↗

Independent functions of Slit-Robo repulsion and Netrin-Frazzled attraction regulate axon crossing at the midline in Drosophila.Semantic proximity Read ↗

Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration.Semantic proximity Read ↗

Slit is the midline repellent for the robo receptor in Drosophila.Semantic proximity Read ↗

Short-range and long-range guidance by Slit and its Robo receptors: a combinatorial code of Robo receptors controls lateral position.Semantic proximity Read ↗

Equivalent Activities of Repulsive Axon Guidance Receptors.Semantic proximity Read ↗

Slit/Robo-mediated axon guidance in Tribolium and Drosophila: divergent genetic programs build insect nervous systems.Semantic proximity Read ↗

Attractive and repulsive functions of Slit are mediated by different receptors in the Drosophila trachea.Semantic proximity Read ↗

FLRT3 is a Robo1-interacting protein that determines Netrin-1 attraction in developing axons.Semantic proximity Read ↗

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