Article
Variants of the serotonin transporter gene, selective serotonin reuptake inhibitors, and bone mineral density in risperidone-treated boys: a reanalysis of data from a cross-sectional study with emphasis on pharmacogenetics.
The Journal of clinical psychiatry - 1 Dec 2011
Calarge Chadi A, Ellingrod Vicki L, Zimmerman Bridget, Bliziotes Michael M, Schlechte Janet A
Abstract excerpt
OBJECTIVE: Selective serotonin reuptake inhibitors (SSRIs) may reduce bone mineral density (BMD). Here, we investigate whether variants of the serotonin transporter-linked polymorphic region (5-HTTLPR) of the serotonin transporter gene moderate this association in boys. METHOD: Between November 2005 and August 2009, medically healthy boys, aged 7 to 17 years, were enrolled in a cross-sectional study exploring the...
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