Article
Otic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathway.
Neuron - 12 Jan 2012
Coate Thomas M, Raft Steven, Zhao Xiumei, Ryan Aimee K, Crenshaw E Bryan, Kelley Matthew W
Abstract excerpt
Peripheral axons from auditory spiral ganglion neurons (SGNs) form an elaborate series of radially and spirally oriented projections that interpret complex aspects of the auditory environment. However, the developmental processes that shape these axon tracts are largely unknown. Radial bundles are comprised of dense SGN fascicles that project through otic mesenchyme to form synapses within the cochlea. Here, we...
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