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Article

Structural and biochemical characterization of HP0315 from Helicobacter pylori as a VapD protein with an endoribonuclease activity.

Nucleic acids research - 1 May 2012

Kwon Ae-Ran, Kim Ji-Hun, Park Sung Jean, Lee Ki-Young, Min Yu-Hong, Im Hookang, Lee Ingyun, Lee Kyu-Yeon, Lee Bong-Jin

Abstract excerpt

VapD-like virulence-associated proteins have been found in many organisms, but little is known about this protein family including the 3D structure of these proteins. Recently, a relationship between the Cas2 family of ribonucleases associated with the CRISPR system of microbial immunity and VapD was suggested. Here, we show for the first time the structure of a member of the VapD family and present a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22241770
DOI: 10.1093/nar/gkr1305
PMCID: PMC3351183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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