Article
Collection of clinical and epidemiological data for genetic linkage and association studies.
Current protocols in human genetics - 1 Jan 2012
Farrer Lindsay, Logue Mark
Abstract excerpt
Modern gene-mapping can include linkage studies, which correlate the presence of disease to broad genomic regions in either small or large family units, and association studies, which can narrow the location of a disease-predisposing trait to a single gene using either case-control or family data. This unit provides an overview of key concepts and presents guidelines for collecting diagnostic, epidemiological,...
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