Article
Recommendations for locus-specific databases and their curation.
Human mutation - 1 Jan 2008
Cotton R G H, Auerbach A D, Beckmann J S, Blumenfeld O O, Brookes A J, Brown A F, Carrera P, Cox D W, Gottlieb B, Greenblatt M S, Hilbert P, Lehvaslaiho H, Liang P, Marsh S, Nebert D W, Povey S, Rossetti S, Scriver C R, Summar M, Tolan D R, Verma I C, Vihinen M, den Dunnen J T
Abstract excerpt
Expert curation and complete collection of mutations in genes that affect human health is essential for proper genetic healthcare and research. Expert curation is given by the curators of gene-specific mutation databases or locus-specific databases (LSDBs). While there are over 700 such databases, they vary in their content, completeness, time available for curation, and the expertise of the curator. Curation and...
Topics
- Computational Biology
- Databases, Genetic
- Expert Testimony
- Genes
- Genetic Markers
- Genetic Variation
- Guidelines as Topic
- Humans
- Mutation