Article
Trapped neutrophil syndrome in a Border Collie dog: clinical, clinico-pathologic, and molecular findings.
The Journal of veterinary medical science - 1 Jun 2012
Mizukami Keijiro, Shoubudani Tomoaki, Nishimoto Seira, Kawamura Ryuta, Yabuki Akira, Yamato Osamu
Abstract excerpt
Trapped neutrophil syndrome (TNS) is an autosomal recessive inherited neutropenia known in Border Collies since the 1990's. Recently, the causative mutation has been identified in the canine VPS13B gene and a DNA-based diagnosis has now become available. The present paper describes clinical and clinico-pathologic findings in a Border Collie with TNS that was molecularly diagnosed for the first time in Japan. In a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.