Article
Multiorgan neutrophilic inflammation in a Border Collie with "trapped" neutrophil syndrome.
Journal of veterinary internal medicine - 1 Nov 2022
Zoto Alyssa, Stecklein Chelsea, Scott Michael A, Bauer Thomas R, Lucidi Cynthia, Cridge Harry
Abstract excerpt
Trapped neutrophil syndrome is a rare congenital disease recognized in Border Collies and is characterized by persistent neutropenia with myeloid hyperplasia. The mechanism of neutropenia has not been described. We document the case of a young Border Collie diagnosed with trapped neutrophil syndrome based on clinical features, blood and bone marrow evaluation, and presence of the associated homozygous mutation....
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