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Article

Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2013

Fung Wai Lun Alan, Naylor Melissa G, Bennett David A, Lange Christoph, Blacker Deborah

Abstract excerpt

BACKGROUND: Genetic association studies of longitudinal cognitive phenotypes are an alternate approach to discovering genetic risk factors for Alzheimer's disease (AD). However, the standard linear mixed model approach is limited in the face of multidimensional longitudinal data and multiple geno...

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PMID: 23650207
DOI: 10.1002/ajmg.b.32151
PMCID: PMC3758806

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23650207-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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