Article
Project among African-Americans to explore risks for schizophrenia (PAARTNERS): evidence for impairment and heritability of neurocognitive functioning in families of schizophrenia patients.
The American journal of psychiatry - 1 Apr 2010
Calkins Monica E, Tepper Ping, Gur Ruben C, Ragland J Daniel, Klei Lambertus, Wiener Howard W, Richard Jan, Savage Robert M, Allen Trina B, O'Jile Judith, Devlin Bernie, Kwentus Joseph, Aliyu Muktar H, Bradford L Dianne, Edwards Neil, Lyons Paul D, Nimgaonkar Vishwajit L, Santos Alberto B, Go Rodney C P, Gur Raquel E
Abstract excerpt
OBJECTIVE: Neurocognitive impairments in schizophrenia are well replicated and widely regarded as candidate endophenotypes that may facilitate understanding of schizophrenia genetics and pathophysiology. The Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS) aims to identify genes underlying liability to schizophrenia. The unprecedented size of its study group (N=1,872), made possible...
Topics
- Adult
- Black or African American
- Bipolar Disorder
- Brain
- Chromosome Mapping
- Cognition Disorders
- Depressive Disorder, Major
- Female